Lesion of cholinergic neurons in nucleus basalis enhances response to general anesthetics
نویسندگان
چکیده
منابع مشابه
Lesion of cholinergic neurons in nucleus basalis enhances response to general anesthetics.
Acetylcholine in the brain has been associated with consciousness and general anesthesia effects. We tested the hypothesis that the integrity of the nucleus basalis magnocellularis (NBM) affects the response to general anesthetics. Cholinergic neurons in NBM were selectively lesioned by bilateral infusion of 192IgG-saporin in adult, male Long-Evans rats, and control rats were infused with salin...
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ژورنال
عنوان ژورنال: Experimental Neurology
سال: 2011
ISSN: 0014-4886
DOI: 10.1016/j.expneurol.2011.01.019